【Product Name】Amoxicillin
【CAS】No. 26787-78-0
【Properties】White or off-white crystalline powder; slightly bitter taste.
【Pharmacological action】
Amoxicillin is a semi-synthetic broad-spectrum penicillin drug, its antibacterial spectrum and antibacterial activity are basically the same as ampicillin, but its acid resistance is stronger than that of ampicillin, and its bactericidal effect is stronger and faster than the latter, but it cannot be used for the treatment of meningitis . The half-life is approximately 61.3 minutes. Amoxicillin is stable under acidic conditions, with a gastrointestinal absorption rate of 90%, which is more rapidly and completely absorbed than ampicillin. Except that the effect on Shigella is worse than that of ampicillin, the other effects are similar.
Amoxicillin has a strong bactericidal effect and a strong ability to penetrate cell walls. After oral administration, the lactam group in the drug molecule is immediately hydrolyzed to form a peptide bond, which is quickly combined with the transpeptidase in the bacteria to inactivate it, cutting off the only way for the bacteria to rely on the transpeptidase to synthesize glycopeptides to build the cell wall, making the bacteria The cells quickly become spherical and rupture and dissolve, and the bacteria eventually swell and die due to the loss of cell walls and continuous water penetration. It has strong antibacterial and bactericidal effects on most pathogenic G+ bacteria and G- bacteria (including cocci and bacilli). Among them, Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, non-penicillinase-producing Staphylococcus, Enterococcus faecalis and other aerobic Gram-positive cocci, Escherichia coli, Proteus mirabilis, Salmonella, and Haemophilus influenzae , Neisseria gonorrhoeae and other aerobic Gram-negative bacteria that do not produce β-lactamase strains and Helicobacter pylori have good antibacterial activity. Hemodialysis can remove part of the drug, but peritoneal dialysis has no effect on removing this product.
Toxicology: not yet clear
[Storage] Keep away from light, cool and dry place
【Validity】Two years
[Packing specification] 5kg/aluminum barrel×2 barrels/box, 25kg/barrel
